Mon, Sep 15, 2025

12 PM – 1 PM EDT (GMT-4)

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Title: Clinical and Translational Science Annual Pilot Award Program 2026
Available Funds: Up to 8 pilot awards at up to $50,000 each
Funding Period: July 1, 2026 - June 30, 2027
Letter of Intent Deadline: Monday, October 20, 2025 at 11:59 PM
Funding Source: NIH National Center for Advancing Translational Sciences

The goals of the CTSC Annual Pilot Program are:
-To foster innovative new clinical and translational research that supports research development to address urgent questions or to develop preliminary data that can provide initial support to establish proof of concept and be used to launch new NIH or other externally-funded research proposals;
-To encourage interdisciplinary teams of investigators that span across CTSC partners to stimulate investigators from other areas to lend their expertise in research in clinical and translational science while developing collaborations or new research avenues;
-To support research collaborations with community partners and organizations; and
-To advance health equity in Northern Ohio through research

Projects must be feasible within the proposed 12-month timeframe, have high methodological and scientific quality, and answer important scientific questions. Up to (8) grants, will be awarded with budgets of up to $50,000 each in direct costs. All research activities must be completed by June 30, 2027.

Priority Areas:

Although applications are welcome in the broad domains of clinical and translational research, we are especially interested in applications covering the following priority areas for 2026 funding:

-Projects addressing clinical translational science; that is, disease agnostic projects that focus on the process of turning research results into real-world applications to improve health
-Innovative, multi-center clinical studies that integrate community and clinical partners to ensure health improvements for all
-Dissemination & Implementation of research evidence and innovation to clinical practice
-Projects that leverage Cosmos or TriNetX
-Projects addressing the health concerns and conditions of rural Ohio
-Innovative use of Artificial Intelligence (AI)
-Innovative Implementation Science methods that promote the uptake of research findings into routine healthcare in clinical or policy contexts
-Interventions at community and/or clinical practices to promote overall health
-Studies on methods to improve the clinical and translational research process
-Projects that focus on the following current topics: gene editing, microbiome, deep learning, robotics in healthcare, drug discovery, advances in medical imaging, improving the reproducibility and reliability of scientific findings

Applicants will first submit a Letter of Intent (LOI) to clearly enunciate the proposed activities that address one or more of these goals with a sustainable design for future application to community health. Applicants submitting a successful LOI will be invited to submit a full proposal.

The call for letters of intent and full 2026 RFA is available on the CTSC website:
https://case.edu/medicine/ctsc/funding-opportunities/annual-pilot

Questions? Contact CTSC Pilot Coordinator, Anna Thornton-Matos: abt11@case.edu

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